Former Syracuse, New York, police detective Carrie Wells has hyperthymesia, a rare medical condition that gives her the ability to visually remember everything. She reluctantly joins the New York City Police Department's Queens homicide unit after her former boyfriend and partner asks for help with solving a case. The move allows her to try to find out the one thing she has been unable to remember, which is what happened the day her sister was murdered.
The search for a wanted shooter triggers a flashback that conflicts with Carrie's perfect memory; the Major Crimes team uncovers a nefarious conspiracy involving trained killers.
Season Finale!
Captain Russo is suspected in the murder of an informant, leading Carrie and Al in a cat-and-mouse game with a corrupt former cop.
Carrie and All receive new information in the cold case of a missing surgeon, putting them on the trail of two con-artists.
Carrie and Al investigate the world of high-stakes video games and corporate espionage after a man is found dead inside a haunted-house attraction.
Suspects are plentiful in a case of a murdered aerospace engineer, the Major Crimes team learns that the victim was working on a billionaire's top secret space mission.